BDBM50517949 CHEMBL4447540
SMILES CCOC(=O)NC(=O)c1ccsc1NC(=O)c1nc2cnccc2s1
InChI Key InChIKey=JCOQDKZVKXILLW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50517949
TargetDecaprenylphosphoryl-beta-D-ribose oxidase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Maharaja Sayajirao University of Baroda
Curated by ChEMBL
The Maharaja Sayajirao University of Baroda
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His6-thioredoxin tagged Mycobacterium tuberculosis H37Rv DprE1 expressed in Escherichia coli BL21(DE3) using FPR as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 30 mins by in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetDecaprenylphosphoryl-beta-D-ribose oxidase(Mycolicibacterium smegmatis (strain ATCC 700084 / ...)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of N-terminal thioredoxin-tagged Mycobacterium smegmatis DprE1 expressed in Escherichia coli BL21(DE3) incubated for 7 days by microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2C9 (unknown origin) using diclofenac as substrate incubated for 20 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair