BDBM50514792 CHEMBL4519240

SMILES CSc1nnc(CCCO)n1-c1cc(C)c(C)c(C)c1

InChI Key InChIKey=WLYAKMVSMAFGQO-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514792   

TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514792(CHEMBL4519240)
Affinity DataKd:  225nMAssay Description:Binding affinity to human TLR8 ectodomain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514792(CHEMBL4519240)
Affinity DataIC50: 30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of ssRNA06-induced NF-kappaB activation measured after 24 hrs by quanti-b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514792(CHEMBL4519240)
Affinity DataIC50: 30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed