BDBM50513878 CHEMBL4542865

SMILES COc1n[nH]c2ncc(cc12)-c1cn(nn1)-c1c(F)ccc(NS(=O)(=O)c2cccc(Br)c2)c1F

InChI Key InChIKey=XBRQXNKVCFFZSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513878   

TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50513878(CHEMBL4542865)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full-length ZAK expressed in baculovirus infected Sf9 insect cells using MBP as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50513878(CHEMBL4542865)
Affinity DataIC50: 272nMAssay Description:Inhibition of recombinant human B-RAF V600E mutant using Ser/Thr3 as substrate after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed