BDBM50511927 CHEMBL4517803

SMILES CCS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3nc[nH]c3n2)cc1

InChI Key InChIKey=SIKZOJIFMBUYSK-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50511927   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50511927(CHEMBL4517803)
Affinity DataKd:  720nMAssay Description:Binding affinity to recombinant human CDK2/CyclinA by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50511927(CHEMBL4517803)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant CDK2/untagged Cyclin A2 (174 to 432 residues) using GST-tagged pRB as substrate preincubated overnight followed by 8 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)