BDBM50511767 CHEMBL4473567

SMILES Cc1cc(N)nc2cc(ccc12)-c1ccc(OCc2ccc(cc2)C#N)c(CN)c1

InChI Key InChIKey=PKODNLRUHCVLDH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511767   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50511767(CHEMBL4473567)
Affinity DataKi:  55nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured for ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50511767(CHEMBL4473567)
Affinity DataKi:  114nMAssay Description:Inhibition of human nNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50511767(CHEMBL4473567)
Affinity DataKi:  8.31E+3nMAssay Description:Inhibition of human eNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50511767(CHEMBL4473567)
Affinity DataKi:  1.35E+4nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed