BDBM50511622 CHEMBL4451702::US12110286, Example 15a

SMILES Cc1cc(C)n(n1)-c1ncc(Cl)c(Nc2ccc3n(C)c(=O)n(CCC(C)(C)O)c3c2)n1

InChI Key InChIKey=UQSUWLFWPLYJIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511622   

TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50511622(CHEMBL4451702 | US12110286, Example 15a)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant His-tagged human BCL6 expressed in Escherichia coli BL21 AI cell incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50511622(CHEMBL4451702 | US12110286, Example 15a)
Affinity DataIC50: 275nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50511622(CHEMBL4451702 | US12110286, Example 15a)
Affinity DataIC50: 245nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In DepthDetails
US Patent