BDBM50511450 CHEMBL4436749

SMILES CC(=O)Nc1cc2NCCCc2c(n1)-c1cccc(C)c1C

InChI Key InChIKey=HKZLJFYLGVHCCO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511450   

TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50511450(CHEMBL4436749)
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50511450(CHEMBL4436749)
Affinity DataKi:  0.00200nMAssay Description:Reversible inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50511450(CHEMBL4436749)
Affinity DataKi:  0.00200nMAssay Description:Reversible inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed