BDBM50511439 CHEMBL4565830

SMILES CNc1cc(nc(N)n1)N1CCCCC1

InChI Key InChIKey=WOSMHMANFDUDQJ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511439   

TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50511439(CHEMBL4565830)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)