BDBM50509872 CHEMBL4447360

SMILES C[C@@H](O)[C@@H](CO)Nc1c(cnn2cc(cc12)-c1ccccc1)C(N)=O

InChI Key InChIKey=PRWQQLFMBINSAW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50509872   

TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509872(CHEMBL4447360)
Affinity DataIC50: 3nMAssay Description:Inhibition of GST-tagged JAK3 (unknown origin) using fluoresceinated peptide as substrate measured after 3 hrs by electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509872(CHEMBL4447360)
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged JAK1 (unknown origin) using fluoresceinated peptide as substrate measured after 3 hrs by electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509872(CHEMBL4447360)
Affinity DataIC50: 34nMAssay Description:Inhibition of Hs-tagged TYK2 (unknown origin) using fluoresceinated peptide as substrate measured after 3 hrs by electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509872(CHEMBL4447360)
Affinity DataIC50: 70nMAssay Description:Inhibition of GST-tagged JAK2 (unknown origin) using fluoresceinated peptide as substrate measured after 3 hrs by electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed