BDBM50509406 CHEMBL4435159
SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(=O)O[C@@H]1[C@@H]2O)O[C@H]3n1cnc2c(N)ncnc12
InChI Key InChIKey=BQZWXNITEWDGCM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50509406
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 170nMAssay Description:Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-...More data for this Ligand-Target Pair
3D Structure (crystal)TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Activation of recombinant human wild-type STING expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase re...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of recombinant human STING haplotype R71H/G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 3.92E+4nMAssay Description:Activation of recombinant human wild-type STING expressed in 293T cells incubated for 7 hrs in absence of digitonin A by bright Glo-luciferase report...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataKd: 2.87E+5nMAssay Description:Binding affinity to wild type human STING (139 to 379 residues) by ITC assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Activation of wild-type human STING expressed in digitonin treated HEK293T cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activati...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 8.51E+4nMAssay Description:Activation of wild-type human STING expressed in HEK293T cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activation measured after ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 1.17E+4nMAssay Description:Activation of wild-type human STING expressed in HEK293T cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activation measured after ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 2.85E+4nMAssay Description:Activation of wild-type human STING expressed in digitonin treated human THP1-Dual cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 2.63E+3nMAssay Description:Activation of wild-type human STING expressed in human THP1-Dual cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activation measure...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: 260nMAssay Description:Agonist activity at human wild type STING expressed in 293T cells by digitonin cell based assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
Curated by ChEMBL
Affinity DataEC50: >1.50E+5nMAssay Description:Agonist activity at human wild type full length STING expressed in 293T cells incubated for 7 hrs by luciferase/cell based assayMore data for this Ligand-Target Pair