BDBM50508823 CHEMBL4544303

SMILES CC(C)(C)OC(C(O)=O)c1c(nc(-c2cnn(Cc3ccccc3)c2)c2ccccc12)-c1ccc2OCCCc2c1

InChI Key InChIKey=OAWCHZSXBRYHKE-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50508823   

TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50508823(CHEMBL4544303)
Affinity DataIC50: 480nMAssay Description:Inhibition of LEDGF/p75-independant HIV1 His/FLAG-tagged integrase expressed in Escherichia coli BL21(DE3) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50508823(CHEMBL4544303)
Affinity DataIC50: 210nMAssay Description:Inhibition of biotinylated-TAR-RNA binding to HIV1 His6-tagged integrase expressed in Escherichia coli BL21(DE3) preincubated for 2 hrs followed by R...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50508823(CHEMBL4544303)
Affinity DataEC50: <1.79E+3nMAssay Description:Induction of HIV1 His/FLAG-tagged integrase hyper-multimerization expressed in Escherichia coli BL21(DE3) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50508823(CHEMBL4544303)
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of LEDGF/p75 binding to HIV1 His/FLAG-tagged integrase expressed in Escherichia coli BL21(DE3) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50508823(CHEMBL4544303)
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibition of LEDGF/p75-dependant HIV1 His/FLAG-tagged integrase expressed in Escherichia coli BL21(DE3) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed