BDBM50507745 CHEMBL4517934

SMILES Oc1nsnc1C(=O)NCC(c1ccccc1)c1ccccc1

InChI Key InChIKey=UXPRYPMZGKJFSU-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50507745   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507745(CHEMBL4517934)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant N-terminal His6-tagged DHODH (159-569 residues) expressed in Escherichia coli BL21(DE3) using DHO as ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50507745(CHEMBL4517934)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) using DHO as substrate prein...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed