BDBM50505277 CHEMBL4553027

SMILES CN(C(=O)CCl)c1cc(Oc2ccccc2OCCn2ccc(=O)[nH]c2=O)c(C)c2cc(ccc12)C#N

InChI Key InChIKey=MXVYCFLMSJUAJE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505277   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505277(CHEMBL4553027)
Affinity DataEC50:  570nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 K103N/Y181C mutant infected in human MT2 cells assessed as reduction in viral infection incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50505277(CHEMBL4553027)
Affinity DataIC50: 480nMAssay Description:Inhibition of HIV-1 reverse transcriptase Y181C mutantMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)