BDBM50482307 CHEMBL1169811

SMILES Cc1cc(cc(C)c1Oc1ccnc(NC2CCN(Cc3ccc(cc3)S(C)(=O)=O)CC2)n1)C#N

InChI Key InChIKey=LPBHCIIMBZNWQE-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50482307   

TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482307(CHEMBL1169811)
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482307(CHEMBL1169811)
Affinity DataIC50: 34nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50482307(CHEMBL1169811)
Affinity DataIC50: 72nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)