BDBM50478026 CHEMBL203420::GW678248::GW8248

SMILES Cc1cc(ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cc(Cl)cc(c1)C#N)S(N)(=O)=O

InChI Key InChIKey=BTOMIMSUTLPSHA-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50478026   

TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50478026(GW678248 | GW8248 | CHEMBL203420)
Affinity DataIC50: 1nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50478026(GW678248 | GW8248 | CHEMBL203420)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase activity using poly (rA)/oligo (dT)15 homopolymer template after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50478026(GW678248 | GW8248 | CHEMBL203420)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50478026(GW678248 | GW8248 | CHEMBL203420)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50478026(GW678248 | GW8248 | CHEMBL203420)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed