BDBM50476647 CHEMBL178593::GRL-98065

SMILES [H][C@@]12CCO[C@]1([H])OC[C@@H]2OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc2OCOc2c1

InChI Key InChIKey=HNEIRZJZTYYDES-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50476647   

TargetProtease(Human immunodeficiency virus type 1)
Kumamoto University Graduate School of Medical and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50476647(CHEMBL178593 | GRL-98065)
Affinity DataKi:  0.0140nMAssay Description:Inhibition of HIV1 protease dimerization in MT2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kumamoto University Graduate School of Medical and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50476647(CHEMBL178593 | GRL-98065)
Affinity DataKi:  0.270nMAssay Description:Inhibition of wild type HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50476647(CHEMBL178593 | GRL-98065)
Affinity DataKi:  0.800nMAssay Description:Inhibition of HIV1 protease V82A mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50476647(CHEMBL178593 | GRL-98065)
Affinity DataKi:  0.850nMAssay Description:Inhibition of HIV1 protease I84V mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50476647(CHEMBL178593 | GRL-98065)
Affinity DataKi:  2.10nMAssay Description:Inhibition of HIV1 protease I50V mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHIV-1 protease(Human immunodeficiency virus)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50476647(CHEMBL178593 | GRL-98065)
Affinity DataKi:  4.60nMAssay Description:Inhibition of HIV1 protease D30N mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed