BDBM50471827 CHEMBL284521

SMILES CC(=O)NCCc1c[nH]c2ccc(F)cc12

InChI Key InChIKey=UDLASALUJLTGJV-UHFFFAOYSA-N

Data  1 KI  3 IC50

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50471827   

TargetMelatonin receptor type 1A/1B(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50471827(CHEMBL284521)
Affinity DataIC50: 295nMAssay Description:inhibitory concentration against Melatonin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50471827(CHEMBL284521)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50471827(CHEMBL284521)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of human Notum using OPTS substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetMelatonin receptor type 1A/1B(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50471827(CHEMBL284521)
Affinity DataKi:  73nMAssay Description:Binding affinity for Melatonin receptor using 2-[125I]iodomelatonin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed