BDBM50468433 CHEMBL4281879::US20230365488, Compound 1x

SMILES OC(=O)[C@H]1[C@@H]([C@@H]([C@H]1c1ccccc1)C(=O)Oc1cccc2ccccc12)c1ccccc1

InChI Key InChIKey=NVOKBONTLOAJKA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50468433   

TargetFatty acid-binding protein, brain(Human)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50468433(CHEMBL4281879 | US20230365488, Compound 1x)
Affinity DataKi:  450nMAssay Description:Displacement of ANS from recombinant human N-terminal His-tagged FABP7 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid-binding protein, brain(Human)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50468433(CHEMBL4281879 | US20230365488, Compound 1x)
Affinity DataKi:  450nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFatty acid-binding protein 5(Human)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50468433(CHEMBL4281879 | US20230365488, Compound 1x)
Affinity DataKi:  790nMAssay Description:Displacement of DAUDA from recombinant human N-terminal His-tagged FABP5 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty acid-binding protein 5(Human)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50468433(CHEMBL4281879 | US20230365488, Compound 1x)
Affinity DataKi:  810nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFABP3 protein(Human)
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM50468433(CHEMBL4281879 | US20230365488, Compound 1x)
Affinity DataKi:  2.70E+3nMAssay Description:Purified FABPs (3 μM) were incubated with fluorescent probe (500 nM) in 30 mM Tris, 100 mM NaCl buffer (pH 7.5). Compounds to be tested were the...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFatty acid-binding protein, heart(Human)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50468433(CHEMBL4281879 | US20230365488, Compound 1x)
Affinity DataKi:  2.82E+3nMAssay Description:Displacement of DAUDA from recombinant human N-terminal His-tagged FABP3 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed