BDBM50467711 CHEMBL4283940

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1CNC[C@@H]1OCP(O)(O)=O

InChI Key InChIKey=LMOOKHOOULQCAZ-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467711   

TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50467711(CHEMBL4283940)
Affinity DataKi:  740nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50467711(CHEMBL4283940)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant N-terminal 6His-tagged HGPRT expressed in Escherichia coli BL21 (DE3) using fixed concentration ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50467711(CHEMBL4283940)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of human HGPRT using fixed concentration of guanine and variable concentrations of PRib-PP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed