BDBM50467630 CHEMBL4291402

SMILES COc1cccc(OCc2cc(C)ccn2)c1-c1ccc2CCNCCc2c1

InChI Key InChIKey=KYANYGKXMNYFBX-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50467630   

TargetTyrosine-protein kinase Lck(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467630(CHEMBL4291402)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467630(CHEMBL4291402)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of Aurora-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467630(CHEMBL4291402)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467630(CHEMBL4291402)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467630(CHEMBL4291402)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467630(CHEMBL4291402)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467630(CHEMBL4291402)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged SYK expressed in baculovirus expression system using Biotin-AAAEEIYGEI as substrate after 60 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467630(CHEMBL4291402)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50467630(CHEMBL4291402)
Affinity DataIC50: 200nMAssay Description:Inhibition of SYK in human Ramos B cells assessed as reduction in anti-human IgM Fab2 fragment-induced ERK phosphorylation preincubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed