BDBM50467334 AIDS-105293::Dapivirine::R-147681::TMC-120
SMILES Cc1cc(C)c(Nc2ccnc(Nc3ccc(cc3)C#N)n2)c(C)c1
InChI Key InChIKey=ILAYIAGXTHKHNT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50467334
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Mcgill University Aids Centre
Curated by ChEMBL
Mcgill University Aids Centre
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of wild-type Human immunodeficiency virus 1 subtype B reverse transcriptase G190A mutant by filte...More data for this Ligand-Target Pair
3D Structure (crystal)TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Mcgill University Aids Centre
Curated by ChEMBL
Mcgill University Aids Centre
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV1 subtype B reverse transcriptase M230L mutant by gel-based primer extension assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of wild type HIV1 subtype B reverse transcriptase by filter-based filtration assayMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Mcgill University Aids Centre
Curated by ChEMBL
Mcgill University Aids Centre
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV1 subtype B reverse transcriptase M230L mutant by filter-based filtration assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of wild type HIV1 subtype B reverse transcriptase by gel-based primer extension assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 322nMAssay Description:Inhibition of Human immunodeficiency virus 1 subtype B reverse transcriptase DNA-dependent DNA polymerase activity by gel-based primer extension assa...More data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Mcgill University Aids Centre
Curated by ChEMBL
Mcgill University Aids Centre
Curated by ChEMBL
Affinity DataIC50: 517nMAssay Description:Inhibition of Human immunodeficiency virus 1 subtype B reverse transcriptase G190A mutant by filter-based filtration assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of wild-type Human immunodeficiency virus 1 subtype B reverse transcriptase Y181C mutant by filte...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of wild-type HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of Human immunodeficiency virus 1 subtype B reverse transcriptase Y181C mutant by filter-based filtration assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of wild-type Human immunodeficiency virus 1 subtype B reverse transcriptase by filter-based filtr...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase L100I mutantMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase Y181C mutantMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase K103N/Y181C double mutantMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase Y188L mutantMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Antwerp
Curated by ChEMBL
University of Antwerp
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase L100I/K103N double mutantMore data for this Ligand-Target Pair