BDBM50464455 CHEMBL4294528::US11565996, Compound Colletochlorin B
SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])c(Cl)c(-[#6])c(-[#6]=O)c1-[#8]
InChI Key InChIKey=JNMQIIRDGREXRG-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50464455
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex
Curated by ChEMBL
University of Sussex
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex
Curated by ChEMBL
University of Sussex
Curated by ChEMBL
Affinity DataIC50: 3.98nMAssay Description:Inhibition of recombinant His-tagged and SUMO-tagged Trypanosoma alternative oxidase expressed in Escherichia coli Rosetta2 using 1-ubiquinol as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 515nMAssay Description:Table 1 summarises the concentration of inhibitor required to reduce the respiration of purified recombinant AOX protein by 50%. Respiration was meas...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Table 1 summarises the concentration of inhibitor required to reduce the respiration of purified recombinant AOX protein by 50%. Respiration was meas...More data for this Ligand-Target Pair