BDBM50464224 CHEMBL4245081

SMILES C[C@@H](Nc1nc(Nc2ccc(F)c(Cl)c2)nc2ccccc12)C1CC1

InChI Key InChIKey=LSMKBOZJAWCJNL-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464224   

TargetSon of sevenless homolog 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50464224(CHEMBL4245081)
Affinity DataEC50:  6.40E+3nMAssay Description:Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)