BDBM50458619 CHEMBL4207266

SMILES C[C@H](CC(O)=O)c1cccc(c1)-n1c(cc2ccc(OC(F)(F)F)cc12)C(N)=O

InChI Key InChIKey=OSJXLDOVNXZNHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50458619   

TargetPhospholipase A2, membrane associated(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458619(CHEMBL4207266)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2 group V(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458619(CHEMBL4207266)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of sPLA2-5 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup 10 secretory phospholipase A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458619(CHEMBL4207266)
Affinity DataIC50: 200nMAssay Description:Inhibition of sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed