BDBM50446479 CHEMBL3110015::US9765054, Compound 50A

SMILES ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccc(cc1)-c1ncc(F)cn1)c1ccccc1

InChI Key InChIKey=QHCRWOYXPXJUJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446479   

TargetHistone deacetylase 3(Human)
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446479(CHEMBL3110015 | US9765054, Compound 50A)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM50446479(CHEMBL3110015 | US9765054, Compound 50A)
Affinity DataIC50: 60nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
In DepthDetails
US Patent