BDBM50440614 CHEMBL2426364
SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(C(=O)N2CCC(CC2)N2CCCC2)c(Nc2ccccc2)c1
InChI Key InChIKey=PQOOIERVZAXHBP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50440614
TargetChromobox protein homolog 7(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CBX7 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Human)
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataKd: 120nMAssay Description:Binding affinity to His-tagged wild type L3MBTL3 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetLethal(3)malignant brain tumor-like protein 3(Human)
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataKd: 120nMAssay Description:Inhibition of L3MBTL3 (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of GST-tagged Jarid1A (unknown origin) using H3K4Me3 as substrate incubated for 30 mins at room temperature followed by incubation under d...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of GST-tagged PHF23 (unknown origin) using H3K4Me3 as substrate incubated for 30 mins at room temperature followed by incubation under dar...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of MBTD1 (130 to 566) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H4K20Me1 as substrate incubated for 30 mins at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of 53BP1 (1485 to 1611) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H4K20Me2 as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
TargetChromobox protein homolog 7(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CBX7 (8 to 62) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H3K9Me3 as substrate incubated for 30 mins at room...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of UHRF1 tandem tudor domain (121 to 286) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H3K9Me3 as substrate incub...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Human)
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 1(Human)
University of North Carolina
Curated by ChEMBL
University of North Carolina
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of His-tagged L3MBTL1 (unknown origin) using H4K20Me1 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetScm-like with four MBT domains protein 1(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SFMBT1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of UHRF1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of L3MBTL1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JARID1A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Human)
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataKd: 120nMAssay Description:Binding affinity to L3MBTL3 (unknown origin) by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataKd: 9.40E+3nMAssay Description:Binding affinity to L3MBTL1 (unknown origin) by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 4(Human)
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of L3MBTL4 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Human)
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PHF23 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Human)
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assayMore data for this Ligand-Target Pair