BDBM50435195 CHEMBL2392921

SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1

InChI Key InChIKey=UZZVALJVPJZKDU-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435195   

TargetMicrotubule-associated protein 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50435195(CHEMBL2392921)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50435195(CHEMBL2392921)
Affinity DataEC50:  200nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)