BDBM50427864 CHEMBL2326359

SMILES Cc1cc(N)nc(CCc2ccc(CCCN)c(CCc3cc(C)cc(N)n3)c2)c1

InChI Key InChIKey=KSYDDSWEHNSQGZ-UHFFFAOYSA-N

Data  3 KI  1 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50427864   

TargetNitric oxide synthase oxygenase(Bacillus subtilis (strain 168))
University of California Irvine

LigandPNGBDBM50427864(CHEMBL2326359)
Affinity DataKd:  8.61E+3nMAssay Description:In short, the difference between the imidazole-bound low-spin peak at 430 nm and the inhibitorbound high-spin peak at 395 nm was measured as a functi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50427864(CHEMBL2326359)
Affinity DataKi:  110nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli using L-arginine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50427864(CHEMBL2326359)
Affinity DataKi:  2.19E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli using L-arginine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50427864(CHEMBL2326359)
Affinity DataKi:  3.34E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli using L-arginine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed