BDBM50426611 CHEMBL2325909

SMILES C[C@@H](NC(=O)c1c[nH]c2ncc(nc12)C1CC1)C(=O)N1CCCCC1

InChI Key InChIKey=STEKXUJMQOKLQV-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50426611   

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426611(CHEMBL2325909)
Affinity DataIC50: 361nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426611(CHEMBL2325909)
Affinity DataIC50: 123nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426611(CHEMBL2325909)
Affinity DataIC50: 69nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)