BDBM50425041 CHEMBL2312565

SMILES C[C@H](CCOc1nccn1C)N(C)C

InChI Key InChIKey=VPQCJEWNIYWNLE-UHFFFAOYSA-N

Data  2 KI  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50425041   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50425041(CHEMBL2312565)
Affinity DataEC50:  2.30E+4nMAssay Description:Agonist activity at human 3:2 alpha4beta2 nAChR expressed in Xenopus laevis oocytes after 1 min by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50425041(CHEMBL2312565)
Affinity DataEC50:  1.20E+3nMAssay Description:Partial agonist activity at human 2:3 alpha4beta2 nAChR expressed in Xenopus laevis oocytes after 1 min by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50425041(CHEMBL2312565)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis AChBP linked to ion channel portion of 5-HT3A receptor expressed in HEK293 cells after 4 hrs b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50425041(CHEMBL2312565)
Affinity DataKi:  1.00E+6nMAssay Description:Displacement of [3H]MLA from rat nAChR alpha7 linked to ion channel portion of 5-HT3A receptor expressed in human tsA-201 cells after 2.5 hrs by scin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed