BDBM50424917 CHEMBL2311578
SMILES Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(cc1)S(C)(=O)=O
InChI Key InChIKey=UJGTUKMAJVCBIS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50424917
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+3nMAssay Description:Inhibition of human p97 in human HeLa cells harboring UbG76V-GFP assessed as accumulation of UbG76V after 6 hrs by microscopic analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Inhibition of human p97 in human HeLa cells harboring UbG76V-GFP assessed as accumulation of UbG76V after 1 hr by microscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human full length Avi-tagged p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2(DE3) using 100 uM ATP as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Covalent inhibition of p97 (unknown origin) ATPase activity incubated for 60 mins in presence of ATP by Biomol Green Reagent based microplate reader ...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of p97 (unknown origin) ATPase activity by Biomol Green Reagent based microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of p97 (unknown origin) ATPase activity by Biomol Green Reagent based microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Inhibition of p97 in human HeLa cells expressing UbG76V-GFP/ODD-Luc assessed as accumulation of Ub-GFP incubated for 6 hrs by confocal microscopic an...More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Inhibition of p97 in human HeLa cells expressing UbG76V-GFP/ODD-Luc assessed as accumulation of Ub-GFP incubated for 6 hrs by confocal microscopic an...More data for this Ligand-Target Pair