BDBM50420775 CHEMBL581146::TCMDC-125324

SMILES Oc1c(cc(Cl)c2cccnc12)C(Nc1ccccn1)c1ccco1

InChI Key InChIKey=SZEZEZHDZJZXEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420775   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Eutropics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50420775(TCMDC-125324 | CHEMBL581146)
Affinity DataIC50: 400nMAssay Description:Inhibition of human GST-tagged Mcl1 expressed in Escherichia coli BL21 using FITC-AHA-MRPEIWIAQELRRIGDEFNA-[NH2] after 20 mins by fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50420775(TCMDC-125324 | CHEMBL581146)
Affinity DataIC50: 800nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed