BDBM50403298 CHEMBL5187263

SMILES C[C@H]1CN(Cc2c(C)c(NC(=O)c3cnc(C)nc3)cn3ccnc23)CCN1C(=O)C1CCCC1

InChI Key InChIKey=ZRXYQWSANXCOEH-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50403298   

TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50403298(CHEMBL5187263)
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at His tagged human RORgammat incubated for 1 hrs in presence of biotinylated co-activator peptide by FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50403298(CHEMBL5187263)
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at His-tagged human RORgammat LBD assessed as inhibition of biotinylated RIP140 co-activator peptide binding incubated for 1...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)