BDBM50402992 CHEMBL2207431

SMILES COc1ccc(-c2cc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)[nH]n2)c(C)c1

InChI Key InChIKey=LATBWIWKSPOPNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402992   

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402992(CHEMBL2207431)
Affinity DataIC50: 4.77E+3nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402992(CHEMBL2207431)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed