BDBM50400802 CHEMBL1235529

SMILES c1cc2cc(c1)S(=O)(=O)NCCCNc3c(cnc(n3)N2)Br

InChI Key InChIKey=AWSQADBSXFTFKL-UHFFFAOYSA-N

Data  6 IC50  2 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50400802   

TargetCyclin-dependent kinase 1(Human)
Universite£

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Universite£

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-G-associated kinase(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)
Affinity DataKd:  112nMAssay Description:Binding affinity to recombinant his tagged GAK (unknown origin) assessed as dissociation constant by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Universite£

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Universite£

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-A receptor 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)
Affinity DataKd:  307nMAssay Description:Binding affinity to recombinant his tagged EPHA2 (D596 to G900 residues) (unknown origin) expressed in Escherichia coli rosetta BL21(D3)-R3-pRARE2 co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50400802(CHEMBL1235529)
Affinity DataEC50:  2.80E+3nMAssay Description:Inhibition of full length EPHA2 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in presence of K4 tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed