BDBM50394684 CHEMBL2165615
SMILES CN(C)C(=O)c1ncc(Oc2cc(cc3oc(C)cc23)C(=O)Nc2cnc(C)cn2)cn1
InChI Key InChIKey=MASKQITXHVYVFL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50394684
Affinity DataEC50: 190nMAssay Description:Activation of human recombinant glucokinase by matrix assay in presence of glucoseMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 188nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Induction of glucokinase translocation from nucleus to cytoplasm in cryopreserved rat hepatocytes after 1 hr by Hoechst staining-based fluorescence m...More data for this Ligand-Target Pair
Affinity DataEC50: 930nMAssay Description:Activation of recombinant human liver glucokinase 2 assessed as reduction in NADH production in presence of 5 mM glucose by G6PDH coupled assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.09E+3nMAssay Description:Activation of recombinant human liver glucokinase 2 assessed as assessed as reduction in Km for glucose in presence of 5 mM glucose by G6PDH coupled ...More data for this Ligand-Target Pair