BDBM50391898 CHEMBL2147538

SMILES CC(C)(N)CNc1nc(cc2cnccc12)-c1ccncc1

InChI Key InChIKey=WNDOFCPEDZYDPL-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50391898   

TargetProtein kinase C eta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human PKCeta assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 967nMAssay Description:Inhibition of recombinant human PKCalpha assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 1(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 21nMAssay Description:Inhibition of ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 2(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant ROCK-2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase N1(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 35nMAssay Description:Inhibition of PKN-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase N2(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant PKN-2 using AKRRRLSSLRA as substrate after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C eta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant PKC-eta after 60 mins by 33P-ATP incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 141nMAssay Description:Inhibition of human recombinant PKC-theta after 60 mins by 33P-ATP incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C beta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 942nMAssay Description:Inhibition of recombinant human PKCbeta1 assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C delta type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human PKCdelta assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C epsilon type(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human PKCepsilon assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50391898(CHEMBL2147538)
Affinity DataIC50: 141nMAssay Description:Inhibition of recombinant human PKCtheta assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed