BDBM50391803 CHEMBL2146888

SMILES NCC1(O)CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=GLTAPZSWBNABCW-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391803   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50391803(CHEMBL2146888)Copy SMILESCopy InChI

Affinity DataIC50: 6.60nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50391803(CHEMBL2146888)Copy SMILESCopy InChI

Affinity DataIC50: 6.60nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL