BDBM50383380 CHEMBL2030553::CHEMBL2070047::US10544104, Compound 28::US11247972, Compound 28::US9765037, Compound 28
SMILES COc1ccc2cc(ccc2c1)-c1nn(CC2CCNCC2)c2ncnc(N)c12
InChI Key InChIKey=MBHHJCMRPHUOAD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50383380
TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization
US Patent
University of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 2.30nMAssay Description:Two types of enzyme assays were developed to follow TgCDPK1 activity, a radiometric scintillation proximity assay measured the labeled γ-phospha...More data for this Ligand-Target Pair
TargetCalcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands(Cryptosporidium parvum (strain Iowa II))
University of Washington Through Its Center For Commercialization
US Patent
University of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 2.30nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetcGMP-dependent protein kinase(Toxoplasma gondii)
University of Washington Through Its Center For Commercialization
US Patent
University of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 4.90nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataIC50: 2.30nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataIC50: 4.90nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataIC50: 4.90nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK-OH as substrate by phosphor imaging methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR using poly glu-Tyr as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CSK using Ac-KKKKEEIYFFF-OH as substrate after 180 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EPHA3 using myelin basic protein as substrate after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p38alpha using myelin basic protein as substrate after 180 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of human LCK using Ac-EIYGEFKKK-OH as substrate after 60 minsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SRC using Ac-EIYGEFKKK-OH as substrate after 60 mins by phosphor imaging methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair