BDBM50381093 CHEMBL2017554

SMILES CCC(O)(CC)c1cc(OCCN2CCOCC2)c2cc([nH]c2c1)-c1n[nH]c2ccsc12

InChI Key InChIKey=PVCKRSKEOOWVMP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50381093   

TargetTyrosine-protein kinase ITK/TSK(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381093(CHEMBL2017554)
Affinity DataIC50: 10.9nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381093(CHEMBL2017554)
Affinity DataIC50: 287nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381093(CHEMBL2017554)
Affinity DataIC50: 162nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381093(CHEMBL2017554)
Affinity DataIC50: 55.7nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed