BDBM50379641 CHEMBL2010809

SMILES NCCNC(=O)c1cncc(c1)-c1cnc(Nc2cc(ccn2)N2CCOCC2)s1

InChI Key InChIKey=TWDABHIMTXVQHI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50379641   

TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50379641(CHEMBL2010809)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of CHK1 by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50379641(CHEMBL2010809)
Affinity DataIC50: 0.0500nMAssay Description:Competitive inhibition of Chk1 in presence of higher ATP levelsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50379641(CHEMBL2010809)
Affinity DataIC50: 340nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed