BDBM50379560 CHEMBL2012881

SMILES OCc1cc2n[nH]c(=O)n2c2cc(ccc12)-c1ccc[nH]1

InChI Key InChIKey=FEKDFTQZRBQDGS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50379560   

TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50379560(CHEMBL2012881)
Affinity DataIC50: 20nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50379560(CHEMBL2012881)
Affinity DataIC50: 319nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50379560(CHEMBL2012881)
Affinity DataIC50: 650nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50379560(CHEMBL2012881)
Affinity DataIC50: 650nMAssay Description:Inhibition of MAP3K7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed