BDBM50378564 CHEMBL145781

SMILES O=c1ccc2ccc(OCc3ccccc3)cc2o1

InChI Key InChIKey=QDLFCBKKECTJSK-UHFFFAOYSA-N

Data  14 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50378564   

TargetAmine oxidase [flavin-containing] A(Human)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BuChE using S-butylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human supersomes MAOBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataIC50: 55.0nMAssay Description:Inhibition of rat brain MAOBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataIC50: 55.0nMAssay Description:Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataIC50: 6.76E+3nMAssay Description:Inhibitory effect on monoamine oxidase A, SD on IC50 values < 10%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelatonin receptor type 1A(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  445nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cell lysates after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 13(Mouse)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 3(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  8.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  1.53E+4nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  2.69E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  5.03E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 6(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi:  9.31E+4nMAssay Description:Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50378564(CHEMBL145781)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed