BDBM50375300 TALAROFLAVONE

SMILES COc1cc2c(C(=O)OC22C(C)CC(=O)C2=O)c(O)c1

InChI Key InChIKey=RHTVEOLOMRDENY-UHFFFAOYSA-N

Data  26 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50375300   

TargetInsulin receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant PLK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant CDK2/CycAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant EPHB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant COTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant AKT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant CDK4/CycD1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase kappa(Human)
Tokyo University of Science

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 8.65E+4nMAssay Description:Inhibition of human DNA polymerase kappaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant CK2alpha1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant B-RAF-V600E mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFocal adhesion kinase 1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant FAKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant ERBB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase beta(Rat)
Tokyo University of Science

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of rat DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed