BDBM50363167 CHEMBL1945559
SMILES Cn1c2c(C(C#N)C3(CCNCC3)NC2=O)c2ccc(Cl)c(Cl)c12
InChI Key InChIKey=OWAWOKKHZNRHGV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 70 hits for monomerid = 50363167
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FYN using ATP as substrateMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 using ATP as substrateMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R using ATP as substrateMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER2 using ATP as substrateMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER1 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HCK using ATP as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PI3Kgamma using ATP as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-kinase beta(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PI4Kbeta using ATP as substrateMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK1 using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of PIM2 using ATP as substrateMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3-beta using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ZAP70 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of YES using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase WNK1(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of WNK1 using ATP as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of VPS34 using ATP as substrateMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TYK2 using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of mTOR using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of PIM3 using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of PIM1 using ATP as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of PI3Kdelta using ATP as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of PI3Kbeta using ATP as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of PI3Kalpha using ATP as substrateMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRalpha using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 2(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAK2 using ATP as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alpha using ATP as substrateMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK4/D1 using ATP as substrateMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 5(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of MK5 using ATP as substrateMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MK2 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LYN using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LCK using ATP as substrateMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of KDR using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK using ATP as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COT1 using ATP as substrateMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cMET using ATP as substrateMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cKIT using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of CK1alpha using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cABL using ATP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AXL using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A using ATP as substrateMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of RET using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Ins1R using ATP as substrateMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PKCalpha using ATP as substrateMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of CaMK2 using ATP as substrateMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of ROCK2 using ATP as substrateMore data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Human)
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Ludwig-Maximilians University of Munich
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RON using ATP as substrateMore data for this Ligand-Target Pair