BDBM50359640 CHEMBL1928872

SMILES O=C1COc2ccc(cc2N1)C1=Nn2cnnc2SC1c1ccccc1

InChI Key InChIKey=PAZOXNQSXSODTC-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50359640   

TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]progesterone from PRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [3H]testosterone from ARMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of [3H]dexomethasone from GRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50: 510nMAssay Description:Antagonist activity at mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359640(CHEMBL1928872)
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]-Aldosterone from human MR overexpressed in FreeStyle 293 cells incubated for 16 hrs by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)