BDBM50358883 CHEMBL1923468

SMILES Clc1ccc2cc(ccc2c1)S(=O)(=O)N[C@H]1CCCN(CC(=O)N2C[C@@H]3C[C@H](C2)c2cccc(=O)n2C3)C1=O

InChI Key InChIKey=FLGSVBQCPOVGER-UHFFFAOYSA-N

Data  8 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50358883   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataIC50: 13nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  4.71nMAssay Description:Inhibition of human factor 10a by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.28E+3nMAssay Description:Inhibition of human TPA by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  3.28E+3nMAssay Description:Inhibition of human alpha-thrombin by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  3.68E+3nMAssay Description:Inhibition of human factor 7a by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.33E+4nMAssay Description:Inhibition of human factor 11a by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.51E+4nMAssay Description:Inhibition of human u-PA by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibition of human plasmin by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  2.25E+4nMAssay Description:Inhibition of human activated protein C by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed