BDBM50357211 177 J.D.::AMINOCAPROIC ACID::Amicar::Aminocaproic

SMILES NCCCCCC(O)=O

InChI Key InChIKey=SLXKOJJOQWFEFD-UHFFFAOYSA-N

Data  2 KI  2 IC50  1 Kd

PDB links: 53 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50357211   

TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50357211(177 J.D. | Amicar | Aminocaproic | AMINOCAPROIC AC...)
Affinity DataIC50: 1.05E+5nMAssay Description:Binding affinity to human full length Glu-plasminogen in buffer assessed as inhibition of interaction with fibrin preincubated for 15 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50357211(177 J.D. | Amicar | Aminocaproic | AMINOCAPROIC AC...)
Affinity DataIC50: 4.00E+4nMAssay Description:Binding affinity to full length Glu-plasminogen in human plasma assessed as inhibition of interaction with fibrin in presence of tPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50357211(177 J.D. | Amicar | Aminocaproic | AMINOCAPROIC AC...)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to human plasminogen K1 domain by ultrafiltration techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProton-coupled amino acid transporter 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50357211(177 J.D. | Amicar | Aminocaproic | AMINOCAPROIC AC...)
Affinity DataKi:  3.50E+7nMAssay Description:Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50357211(177 J.D. | Amicar | Aminocaproic | AMINOCAPROIC AC...)
Affinity DataKi:  5.30E+7nMAssay Description:Inhibition of plasmin (unknown origin) assessed as reduction in amidolytic activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)