BDBM50356573 CHEMBL1909991

SMILES COc1ccccc1N1Cc2c(nc(C)c(CN)c2-c2ccc(Cl)cc2Cl)C1=O

InChI Key InChIKey=YFKUZVBMNGNFRI-UHFFFAOYSA-N

Data  9 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50356573   

TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP3A4 in presence of the substrate 7-bezyloxy-4-trifluoromethyl coumarinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP3A4 in presence of the substrate 7-bezyloxy-4-trifluoromethyl coumarinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CYP3A4 in presence of the substrate 7-bezyloxy-4-trifluoromethyl coumarinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataKi:  3nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataKi:  3nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataKi:  3nMAssay Description:Non-competitive inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDipeptidyl peptidase 8(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataKi:  886nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataKi:  886nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataKi:  1.09E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50356573(CHEMBL1909991)
Affinity DataKi:  1.32E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed