BDBM50354410 CHEMBL1836848

SMILES Clc1cc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C2CC2)ccc1C(=O)N1CCOCC1

InChI Key InChIKey=WMGUFRGUWSBJIK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50354410   

TargetAurora kinase B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354410(CHEMBL1836848)
Affinity DataIC50: 8.48E+3nMAssay Description:Inhibition of AurBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354410(CHEMBL1836848)
Affinity DataIC50: 600nMAssay Description:Inhibition of phosphorylation of SAM68 in 293 WT-PTK6 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354410(CHEMBL1836848)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354410(CHEMBL1836848)
Affinity DataIC50: 124nMAssay Description:Inhibition of BRK pretreated for 30 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed